Просмотров: 10840

Толстой Пётр Михайлович

Обновлено 12 Апр. 2023 г.

Пётр Михайлович Толстой

Заведующий кафедрой физической органической химии,
д.х.н., профессор кафедры физической органической химии, комната 2150

Телефоны: (раб.) (812) 3636899, (моб.) +7 (921) 4308191

e-mail: peter.tolstoy@spbu.ru

Почтовый адрес: Институт химии
Россия, 198504 Санкт-Петербург, Университетский пр., д. 26

Биография

2019–... профессор кафедры физической химии

2018–2019 доцент кафедры физической химии

2012–2018 доцент кафедры физической органической химии

2011–2018 директор РЦ "Магнитно-резонансные методы исследования" Научного парка

2010–2011 научный сотрудник Института нелинейной оптики и короткоимпульсной спектроскопии им. Макса Борна, Адлерсхоф, Германия

2008–2010 руководитель научной группы в Институте химии и биохимии Свободного университета Берлина, Германия

2004–2008 постдок в группе проф. Х.-Х. Лимбаха, Институт химии и биохимии Свободного университета Берлина, Германия

2000–2004 аспирантура под руководством проф. Г.С. Денисова, кафедра молекулярной спектроскопии, СПбГУ; тема работы "Определение положения протона в сильных водородных связях по изотопным эффектам в спектрах ЯМР ¹³C в растворах"

1994–2000 обучение на физическом факультете СПбГУ

Стипендия им. Эйлера (2000), стипендия им. Кекуле (2001), руководитель грантов РФФИ (2001, 2003), стипендия GRK DAAD (2004), грант FUB (2005), грант DFG (2007), руководитель грантов РФФИ (2011, 2014)

Преподавание

Магнитный резонанс (бакалавриат; 28 часов)
Magnetic Resonance and its Applicationsin Chemistry (магистратура; 16 часов; на английском языке)
~~Molecular Spectroscopy~~ (28 часов; курс читался в Свободном университете Берлина)
~~Quantum Mechanics in Chemistry~~ (42 часа; курс читался в Свободном университете Берлина)
~~Mathematical Principles of NMR~~ (28 часов; курс читался в Свободном университете Берлина)

Избранные публикации

P. Schah-Mohammedi, I.G. Shenderovich, C. Detering, H.-H. Limbach, P.M. Tolstoy, S.N. Smirnov, G.S. Denisov, N.S. Golubev, "Hydrogen/Deuterium Isotope Effects on NMR Chemical Shifts of Formally Symmetric Complexes with a Strong Intermolecular Hydrogen Bond in Liquid Solutions at 100-150K", J. Am. Chem. Soc., 2000, 122, 12878–12879.
I.G. Shenderovich, P.M. Tolstoy, N.S. Golubev, S.N. Smirnov, G.S. Denisov, H.-H. Limbach, "Low-Temperature NMR Studies of the Structure and Dynamics of a Novel Series of Acid-Base Complexes of HF with Collidine Exhibiting Scalar Couplings Across Hydrogen Bonds", J. Am. Chem. Soc., 2003, 125, 11710–11720.
P.M. Tolstoy, P. Schah-Mohammedi, S.N. Smirnov, N.S. Golubev, G.S. Denisov, H.-H. Limbach, "Characterization of Fluxional Hydrogen-Bonded Complexes of Acetic Acid and Acetate by NMR: Geometries and Isotope and Solvent Effects", J. Am. Chem. Soc., 2004, 126, 5621–5634.
H.-H. Limbach, M. Pietrzak, S. Sharif, P.M. Tolstoy, I.G. Shenderovich, S.N. Smirnov, N.S. Golubev, G.S. Denisov, “NMR Parameters and Geometries of OHN and ODN Hydrogen Bonds of Pyridine-Acid Complexes”, Chem. Eur. J., 2004, 10, 5195–5204.
S. Sharif, E. Fogle, M.D. Toney, G.S. Denisov, I.G. Shenderovich, G. Buntkowsky, P.M. Tolstoy, M. Chan Huot, H.-H. Limbach, "NMR Localization of Protons in Critical Enzyme Hydrogen Bonds", J. Am. Chem. Soc., 2007, 129, 9558–9559.
P.M. Tolstoy, B. Koeppe, G.S. Denisov, H.-H. Limbach, "Combined NMR/UV-Vis Spectroscopy in the Liquid State: Study of the Geometries of Strong OHO Hydrogen Bonds of Phenols with Carboxylic Acids", Angew. Chem. Int. Ed., 2009, 48, 5745–5747.
H.-H. Limbach, P.M. Tolstoy, N. Perez-Hernandez, J. Guo, I.G. Shenderovich, G.S. Denisov, “OHO Hydrogen Bond Geometries and NMR Chemical Shifts: From Equilibrium Structures to Geometric H/D Isotope Effects with Applications for Water, Protonated Water and Compressed Ice”, Israel J. Chem., 2009, 49, 199–216.
N.S. Golubev, C.Detering, S.N. Smirnov, I.G. Shenderovich, G.S. Denisov, H.-H. Limbach, P.M. Tolstoy, “H/D Isotope Effects on NMR Chemical Shifts of Nuclei Involved in a Hydrogen Bridge of Hydrogen Iso-cyanide Complexes with Fluoride Anion”, Phys. Chem. Chem. Phys., 2009, 11, 5154–5159.
M. Pietrzak, J.P. Wehling, S. Kong, P.M. Tolstoy, I.G. Shenderovich, C. Lopez, R.M. Claramunt, J. Elguero, G.S. Denisov, H.-H. Limbach, “Symmetrization of Cationic Hydrogen Bridges of Protonated Sponges Induced by Solvent and Counteranion Interactions as Revealed by NMR Spectroscopy”, Chem. Eur. J., 2010, 16, 1679–1690.
S.B. Lesnichin, P.M. Tolstoy, H.H. Limbach, I.G. Shenderovich, “Counteranion-dependent mechanisms of intramolecular proton transfer in aprotic solution”, Phys. Chem. Chem. Phys., 2010, 12, 10373–10379.
M. Chan-Huot, S. Sharif, P.M. Tolstoy, M.D. Toney, H.-H. Limbach, “NMR Studies of the Stability, Protonation States and Tautomerism of 13C and 15N Labeled Aldimines of the Coenzyme Pyridoxal 5’-phosphate in Water”, Biochemistry, 2010, 49, 10818–10830.
D. Ajami, P.M. Tolstoy, H. Dube, S. Odermatt, B. Koeppe, J. Guo, H.-H. Limbach, J. Rebek Jr., “Compressed Hydrogen Bonds Isolated in Encapsulation Complexes”, Angew. Chem. Int. Ed., 2011, 50, 528–531.
J. Guo, B. Koeppe, P.M. Tolstoy, “Trimethylglycine Complexes with Carboxylic Acids and HF: Solvation by Polar Aprotic Solvent”, Phys. Chem. Chem. Phys., 2011, 13, 2335–2341.
B. Koeppe, P.M. Tolstoy, E.T. J. Nibbering, T. Elsaesser, “Two-dimensional UV-vis/NMR Correlational Spectroscopy: A Heterospectral Signal Assignment of Hydrogen-Bonded Complexes”, J. Phys. Chem. Lett., 2011, 2, 1106–1110.
B. Koeppe, P.M. Tolstoy, H.-H. Limbach, “Reaction Pathways of Proton Transfer in Hydrogen bonded Phenol-Carboxylate Complexes explored by UVNMR”, J. Am. Chem. Soc., 2011, 133, 7897–7908.
G.A. Silantyev, O.A. Filippov, P.M. Tolstoy, N.V. Belkova, L.M. Epstein, K. Weisz, E.S. Shubina, „Hydrogen bonding and proton transfer to ruthenium hydride complex CpRuH(dppe): metal and hydride dichotomy”, Inorg. Chem., 2013, 52, 1787–1797.
B. Koeppe, J. Guo, P.M. Tolstoy, G.S. Denisov, H.-H. Limbach, “Solvent and H/D Isotope Effects on the Proton Transfer Pathways in Heteroconjugated Hydrogen-Bonded Phenol-Carboxylic Acid Anions Observed by Combined UV–vis and NMR Spectroscopy”, J. Am. Chem. Soc., 2013, 135, 7553–7566.
M. Chan-Huot, A. Dos, R. Zander, S. Sharif, P.M. Tolstoy, S. Compton, E. Fogle, M.D. Toney, I.G. Shenderovich, G.S. Denisov, H.-H. Limbach, “NMR Studies of Protonation and Hydrogen Bond States of Internal Aldimines of Pyridoxal 5’-Phosphate Acid-Base in Alanine Racemase, Aspartate Aminotransferase, and Poly-L-lysine”, J. Am. Chem. Soc., 2013, 135, 18160–18175.
A. Miroslavov, Y. Polotskii, V. Gurzhiy, A. Ivanov, A. Lumpov, M. Tyupina, G. Sidorenko, P. Tolstoy, D. Maltsev, D. Suglobov, “Technetium and Rhenium Pentacarbonyl Complexes with C2 and C11 ω-Isocyanocarboxylic Acid Esters”, Inorg. Chem., 2014, 53, 7861–7869.
I.G. Shenderovich, S.B. Lesnichin, C. Tu, D.N. Silverman, P.M. Tolstoy, G.S. Denisov, H.-H. Limbach, “NMR Studies of Active Site Properties of Human Carbonic Anhydrase II using 15N labeled 4-Methylimidazole as a Local Probe and Histidine Hydrogen Bond Correlations”, Chem. Eur. J., 2015, 21, 2915–2929.
S. Pylaeva, C. Allolio, B. Koeppe, G.S. Denisov, H.-H. Limbach, D. Sebastiani, P.M. Tolstoy, “Proton transfer in a short hydrogen bonded complex caused by solvation shell fluctuations: an ab initio MD and NMR/UV study of an (OHO)-bonded system”, Phys. Chem. Chem. Phys., 2015, 17, 4634–4644.
H.-H. Limbach, G.S. Denisov, I.G. Shenderovich, P.M. Tolstoy, “Proton Tautomerism in Systems of Increasing Complexity: Examples from Organic Molecules to Enzymes” in “Tautomerism: Concepts and Applications in Science and Technology”, Edited by Liudmil Antonov, 2016, John Wiley and Sons.
T.V. Serebryanskaya, A.S. Novikov, P.V. Gushchin, M. Haukka, R.E. Asfin, P.M. Tolstoy, V.Yu. Kukushkin, “Combined structural, theoretical and spectroscopic study of C–H···Cl− interactions of haloalkanes with chloride anion in solid state”, Phys. Chem. Chem. Phys., 2016, 18, 14104–14112.
B. Koeppe, S.A. Pylaeva, C. Allolio, D. Sebastiani, E.T.J. Nibbering, G.S. Denisov, H.-H. Limbach, P.M. Tolstoy, “Polar solvent fluctuations drive proton transfer in hydrogen bonded complexes of carboxylic acid with pyridines: NMR, IR and ab initio MD study”, Phys. Chem. Chem. Phys., 2016, accepted. DOI: 10.1039/C6CP06677A.
S.A. Pylaeva, H. Elgabarty, D. Sebastiani, P.M. Tolstoy, “Symmetry and dynamics of FHF– anion in vacuum, in CD₂Cl₂ and in CCl₄. Ab initio MD study of fluctuating solvent-solute hydrogen and halogen bonds”, Phys. Chem. Chem. Phys. 2017, accepted.